Restriction Enzymes - Endonucleases

SibEnzyme US, LLC is delighted to offer new, site-specific endonucleases Bls I, Gla I, Glu I and Mal I

These enzymes belong to a new type of 5mC site-specific DNA endonucleases discovered and characterized at SibEnzyme. Bls I, Gla I and Glu I recognize and cleave only the DNA sequences with two and more 5-methylcytosines and do not cleave unmethylated DNA. These enzymes may be used for epigenetic studies and are available exclusively at SibEnzyme.

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Enzyme	Prototype	Recognition Sequence	Cat.No. Package, u.a. Price* in USD
Bls I	Bls I	G(5mC)N^GC (5mC)G^N(5mC)G	E533 100 140.00 E534 500 560.00
Gla I	Gla I	G(5mC)^G(5mC) (5mC)G^(5mC)G	E493 100 150.00 E494 500 600.00
Glu I	Glu I	(5mC)G(5mC)^NG(5mC)G G(5mC)GN^(5mC)G(5mC)	E519 100 140.00 E520 500 560.00
Mal I	Dpn I	G(mA)^TC CT^(mA)G	E489 50 7.50 E490 250 30.00